|
|
|||
|
|
|
|||
|
Main page Contacts Themes Archive  Themes Subscription Information to authors Editorial board Mobile version In Ukrainian Export citations UNIMARC BibTeX RIS |  |
Features of Fetal Bone Organ Culture Development under Space Flight Conditions
Fetal mouse metatarsals cultured for 4 days onboard international space laboratory IML-1 (STS-42) were investigated using light microscopy and electron microscopy combined with X-ray microanalysis. Bones cultured in microgravity were equal in length to both ground and inflight (1 g) controls. Three zones: epiphyseal, proliferative, and hypertrophic chondrocytes were distinguished and measured in metatarsals isolated from 16-day-old fetuses. In bone cultures exposed to microgravity, hypertrophic zone tended to decrease and epiphyseal area was increased compared to controls. Proliferative zone has equal length both in bones cultured under microgravity and in controls. The same tendency was observed in bone cultures from 17-day-old fetuses. Metatarsals cultured in microgravity have less spreading calcification zone of diaphysis in comparison with both controls. The results suggest that maturation of chondrocytes and calcification of cartilage, but not cell proliferation, are microgravity sensitive processes in developing bones isolated from the organism.
Tsitologiya i Genetika 2002, vol. 36, no. 2, pp. 60-67
|
|
|||
| Coded & Designed by Volodymyr Duplij | Modified 28.05.23 | ||
