TSitologiya i Genetika 2021, vol. 55, no. 3, 58-75
Cytology and Genetics 2021, vol. 55, no. 3, 256–269, doi: https://www.doi.org/10.3103/S0095452721030099

Mobile genetic elements (MGE) of bacteria and their hierarchy

Skliar T., Kurahina N., Lavrentieva K., Burlaka V., Lykholat T., Lykholat O.

  1. Oles Honchar Dnipro National University, 72, Gagarina prosp., Dnipro 49010
  2. University of Customs and Finance, 2/4, Volodymyra Vernadskoho Str., Dnipro, Ukraine

SUMMARY. This review highlights mobile genetic elements (MGE) of bacteria, widespread in different genomes. MGE encode the functions that are insignificant for bacteria yet give them some advantages (adjusting to new environmental conditions, «invading» and colonizing a new host, etc.) and play a relevant role in ensuring the mobility of genomes. The article summarizes and analyzes current data on mobile genetic elements of bacteria and the specificities of their interaction, reviews the mechanisms of mobility of genetic elements and incompatibility of bacteriophages, plasmids, and restriction-modification systems. It also underscores the classification and the mechanisms of functioning for restriction-modification systems in bacterial cells. The attention is focused on the incompatibility of mobile genetic elements, as it reflects their individual and egoistic nature and is even used as a basis to classify some of them. Mobile genetic elements are viewed both as promising biotechnological objects for cloning and gene expression, and a «tool» in studying many fundamental issues.

Keywords: mobile genetic elements, pathogenicity islands, bacteriophages, plasmids, RM-systems, incompatibility

TSitologiya i Genetika
2021, vol. 55, no. 3, 58-75

Current Issue
Cytology and Genetics
2021, vol. 55, no. 3, 256–269,
doi: 10.3103/S0095452721030099

Full text and supplemented materials


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