125 years of virology and ascentof biotechnologies based on viral expression

Giritch A., Klimyuk V., Gleba Y.

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SUMMARY. The study of viruses lasts for more than a century since their discovery in 1892. In recent decades, viruses are also being actively exploited as a biotechnological tool. Plant-virus-driven transient expression of heterologous proteins is an actively developing production platform; it is the basis of several industrial processes that are currently being used for the production of multiple recombinant proteins. Viral vectors have also become useful tools for research. Viral vectors delivered by Agrobacterium (magnifection) provide for high pro-tein yield, rapid scale up and fast manufacturing. In this review, we explore modern approaches for bio technological production of recombinant proteins in plants using viral vectors.

Tsitologiya i Genetika 2017, vol. 51, no. 2, pp. 19-39

E-mail: gleba nomadbioscience.com

Giritch A., Klimyuk V., Gleba Y. 125 years of virology and ascentof biotechnologies based on viral expression, Tsitol Genet., 2017, vol. 51, no. 2, pp. 19-39.

In "Cytology and Genetics":
A. Giritch, V. Klimyuk, Y. Gleba 125 years of virology and ascent of biotechnologies based on viral expressio, Cytol Genet., 2017, vol. 51, no. 2, pp. 87–102
DOI: 10.3103/S0095452717020037