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Mitochondrial Evolution

Litoshenko A. Ya.


Until recently, the origin and evolution of mitochondria was explained by the serial endosymbiosis hypothesis. This hypothesis posits that contemporary mitochondria are the direct descendants of a bacterial endosymbiont, which was settled in a nucleus-containing amitochondriate host cell. Results of the mitochondrial gene sequences support a monophyletic origin of the mitochondria from a single eubacterial ancestor shared with a subdivision of the a-Proteobacteria. In recent years, the complete sequences of the vast variety of mitochondrial and eubacterial genomes were determined. These data indicate that the mitochondrial genome evolved from a common ancestor of all extant eukaryotes and assume a possibility that the mitochondrial and nuclear constituents of the eukaryotic cell originated simultaneously.

Tsitologiya i Genetika 2002, vol. 36, no. 5, pp. 49-57

Litoshenko A. Ya. Mitochondrial Evolution, Tsitol Genet., 2002, vol. 36, no. 5, pp. 49-57.

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