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The mechanisms of the increase in the amount of lipofuscin in the cells during agingReview The literary data concerning the mechanisms of an increase of lipofuscin amount in cells are reviewed. The paper contains information about the properties of lipofuscin inclusions, the influence of autophagocytosis, intralysosomal degradation, and exocytosis on lipofuscin content in cells. The question of the possibility of complete elimination of autophagocytosed material is discussed.
Tsitologiya i Genetika 1997, vol. 31, no. 5, pp. 91-100
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