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Peculiarities of Proliferation Stimulation of the Cultivated Chick Embryo Cells during Replanting
The growth rate of chick embryo cells in slowly proliferating cultures is activated after substitution of conditioned medium by fresh one with serum. After cell replanting, the stimulation of cell proliferation takes place in both media with the same effectiveness. In serum-less medium replanted cells do not adhere to glass and die. The results suggest that cells reversibly lose their dependence upon serum growth factors and population density, as a result of replanting, but retain anchorage-dependence for growth.
Tsitologiya i Genetika 1989, vol. 23, no. 5, pp. 30-34
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