Cytology and Genetics ,
vol. ,
no. , ,
doi: https://www.doi.org/
SUMMARY. One of the main factors that can exert influence on the position and rate of skin regeneration process is IGF-1. Morphological and molecular biological studies of skin wounds of FVB wild-type mice and transgenic animals K14/mIGF-1 with streptozotocin-induced diabetes were carried out. An increase of IGF-1 expression, area and thickness of the regenerating epithelium, the number of Mac-1+ cells in the wound in transgenic animals compared with wild-type was shown.
Keywords: skin, wound healing, diabetes, IGF-1, the expression
