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Expression of Cftr, Nfkb1 and Ocln genes during the restoration of skin integrity

Huet ., Dvorshchenko ., Grebinyk D., Beregova T., Ostapchenko L.


SUMMARY. The decrease in the expression levels of Ctfr and Ocln genes was shown while healing planar full-thickness excisional wounds as well as purulonecrotic skin wounds in rats on the background of the increase in the expression level of Nfkb1. The restoration of Ocln gene expression might be mediated by the increase of Ctfr gene expression caused by the decrease in Nfkb1 mRNA level. When melanin was applied under these conditions, the values of Ctfr and Ocln expression reached the corresponding values for the control group of rats faster without the Nfkb1 hyperexpression during the recovery of skin integrity.

Tsitologiya i Genetika 2022, vol. 56, no. 3, pp. 35-43

  • Educational and Scientific Center Institute of Biology and Medicine Taras Shevchenko National University of Kyiv, 64/13, Volodymyrska Str., Kyiv, 01601

E-mail: alevtina.dranitsina

Huet ., Dvorshchenko ., Grebinyk D., Beregova T., Ostapchenko L. Expression of Cftr
, Nfkb1 and Ocln genes during the restoration of skin integrity, Tsitol Genet., 2022, vol. 56, no. 3, pp. 35-43.

In "Cytology and Genetics":
A. S. Huet, K. O. Dvorshchenko, D. M. Grebinyk, T. V. Beregova & L. I. Ostapchenko Expression of the Cftr, Nfkb1, and Ocln Genes during Restoration of Skin Integrity, Cytol Genet., 2022, vol. 56, no. 3, pp. 236243
DOI: 10.3103/S0095452722030148


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