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Double punh: hepatitis C in patients with genetic defects of iron metabolism

Danilenko N.G., Siniauskaya M.G., Lukashyk S.P., Karpov I.A., Davydenko O.G.


SUMMARY. The review deals with peculiarities of chronic virus hepatitis C in patients with mutations in HFE gene, which lead to impaired iron metabolism. We discuss the sensitivity of patients having HFE mutations to: virus C invasion; progress of hepatic pathological processes during chronic hepatitis C, including the most severe complications liver cirrhosis and hepatocellular carcinoma; HCV therapy.

Key words: HFE mutations, hepatitis C virus, chronic virus infection, iron overload

Tsitologiya i Genetika 2019, vol. 53, no. 5, pp. 75-89

E-mail: cytoplasmic, svetlanalukashik

Danilenko N.G., Siniauskaya M.G., Lukashyk S.P., Karpov I.A., Davydenko O.G. Double punh: hepatitis C in patients with genetic defects of iron metabolism, Tsitol Genet., 2019, vol. 53, no. 5, pp. 75-89.

In "Cytology and Genetics":
N. G. Danilenko, M. G. Siniauskaya, S. P. Lukashyk, I. A. Karpov, O. G. Davydenko Double Punch: Hepatitis C in Patients with Genetic Defects of Iron Metabolism, Cytol Genet., 2019, vol. 53, no. 5, pp. 407417
DOI: 10.3103/S0095452719050062


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