ISSN 0564-3783  



Main page
Contacts
Themes
Archive  
Themes
Subscription
Information to authors
Editorial board
Mobile version


In Ukrainian

Export citations
UNIMARC
BibTeX
RIS





The functioning of glia and neurodegeneration in Drosophila melanogaster

Mohylyak ².²., Chernyk Ya.².

 




SUMMARY. A view at the importance of glial tissue has undergone major changes during the years of research. Regarded as «brain cellular glue» at the beginning, it becomes recognized as one of great importance for development and support of the brain. Glial cells are responsible for many critical processes in the nervous system, among them: navigation signaling for axon growth, electrical insulation of neurons, boundaries formation between brain and hemolymph, control of extracellular homeostasis and physiological brain functioning. To clarify many molecular aspects of neurodegeneration, modern science increasingly drawn to D. melanogaster as a useful model, as it has a number of advantages. Drosophila neurodegenerative mutant swiss cheese (sws) shows degeneration of the neurons and ensheathing glia of the optic lobes and SWS protein is important for maintenance functionality and integrity of the fly brain. In this review, we focus on the importance of glial cells for development and function of the adult insect brain, and on the characterization of the sws gene and it expression in neuronal and glial cells.

Tsitologiya i Genetika 2017, vol. 51, no. 3, pp. 66-78

E-mail: yacher54 gmail.com

Mohylyak ².²., Chernyk Ya.². The functioning of glia and neurodegeneration in Drosophila melanogaster, Tsitol Genet., 2017, vol. 51, no. 3, pp. 66-78.

In "Cytology and Genetics":
I. I. Mohylyak, Ya. I. Chernyk Functioning of glia and neurodegeneration in Drosophila melanogaster, Cytol Genet., 2017, vol. 51, no. 3, pp. 202–213
DOI: 10.3103/S0095452717030094


Copyright© ICBGE 2002-2023 Coded & Designed by Volodymyr Duplij Modified 01.06.23