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The possible role of polyphosphatases in yeast sensitivity to electromagnetic fields of DCS-1800
SUMMARY. The perception of an influence of electromagnetic radiation is one of the most intriguing issues that concern the fundamental problems of interaction of living matter with the factors of physical nature. The polyphosphates are seemed to be such receptors. The purpose was to evaluate the role of polyphosphatases PPN1 and PPX1 in the yeast Saccharomyces cerevisiae cellular response to the action of electromagnetic field (EMF) 1871†MHz generated by base stations of DCS-1800. Six-week exposure at energy flux densities 0.1Ц10†W/m2 was used. The corresponding values of specific adsorption rate (SAR) were 0.0075Ц1.5 W/kg. EMF caused the disruption of cellular physiological and metabolic functions, changed their antibiotic resistance and led to irreversible changes in their genome. Low doses of EMF caused the strongest biological reactions. Deficiency in ppn1 and ppx1 genes resulted in reduced adaptive potency of cells and increased sensitivity to EMF action. This study shown that both polyphosphatases (PPN1 and PPX1) are necessary unites for adequate cellular response onto the action of non-ionizing EMF 1871 MHz.
Key words: polyphosphatases, Saccharomyces cerevisiae, electromagnetic fields, GSM, DCS-1800
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|Coded & Designed by Volodymyr Duplij||Modified 25.09.21|