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The effects of polymorphisms in growth hormone and growth hormone receptor genes on production and reproduction traits in aberdeen-angus cattle (Bos taurus L., 1758)
SUMMARY. It was found the relation between individual genotypes and allelic variants of SNPs g.2141C>G of growth hormone gene, g.914T>A and g.257A>G of growth hormone receptor gene with growth and reproduction traits and to evaluate the population-genetic structure in Aberdeen-Angus cattle (Bos taurus L., 1758) sample of Eastern Ukraine according SNPs studied was evaluated. Allele C of SNP g.2141C>G has a positive correlation with birth weight, body stature, bigger rump, udder and total exterior evaluation score, shorter calving interval and better calve birth weight and negative correlation with calve average daily gain. Allele T of SNP g.914T>A has positive correlation with the muscle and udder size; live weight in each age, average daily gain, weight and average daily gain of calves born conform to the principle AA>TT≥TA. SNP g.257A>G showed a positive correlation for G allele with muscle size. The population is in equilibrium for SNPs g.2141C>G and g.257A>G, and in disequilibrium for SNP g.914T>A. The analysis showed no linkage disequilibrium between SNPs g.914T>A and g.257A>G (Dʹ = 0,108; r2 = 0,004). Inbreeding coefficient FST in Aberdeen-Angus group studied was 16,1 %.
Key words: SNP, GH gene, GHR gene, g.2141C>G, g.257A>G, g.914T>A, Aberdeen-Angus
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