Cytology and Genetics 2016,
vol. 50,
no. 6, 366–371,
doi: https://www.doi.org/10.3103/S0095452716060098
SUMMARY. The review presents data on the basic molecular ge-netic mechanisms of formation of papillary thyroid carcinoma. The participation of ionizing radiation in the cancer pathogenesis was analyzed. The role of tu-mor microenvironment, inflammation and nuclear trans-cription factor NF-κB in the initiation and development of papillary thyroid carcinoma was shown.
Keywords: thyroid, papillary carcinoma, oncogenes, ionizing radiation, inflammation, NF-κB
щитоподібна залоза, папілярна карцинома, онкогени, іонізуюча радіація, запалення, NF-κB
