DNA methylation in Drosophila melanogaster may depend on lineage heterogeneity

Redchuk T.A., Rozhok A.I., Zhuk O.W., Kozeretska I.A., Mousseau T.A.

DNA methylation has been discovered in Drosophila only recently. Current evidence indicates that de novo methylation patterns in drosophila are maintained in a different way compared to vertebrates and plants. As the genomic role and determinants of DNA methylation are poorly understood in invertebrates, its link with several factors has been suggested. In this study, we tested for the putative link between DNA methylation patterns in Drosophila melanogaster and radiation or the activity of P transposon. Neither of the links was apparent from the results, however, we obtained some hints on a possible link between DNA methylation pattern and genomic heterogeneity of fly lineages.

Key words: Drosophila melanogaster, P element, DNA methylation, radioactive contamination

Tsitologiya i Genetika 2012, vol. 46, no. 1, pp. 75-79

• O.V. Palladin Institute of Biochemistry of NAS of Ukraine, Kyiv
• Taras Shevchenko National University of Kyiv
• University of South Carolina, Columbia, USA

E-mail: arozhok gmail.com

Redchuk T.A., Rozhok A.I., Zhuk O.W., Kozeretska I.A., Mousseau T.A. DNA methylation in Drosophila melanogaster may depend on lineage heterogeneity, Tsitol Genet., 2012, vol. 46, no. 1, pp. 75-79.