Preservation of parenchymal and stromal progenitors in cryopreserved human fetal liver

In this paper we show presents of viable population of hepatoblasts, endodermal blasts, endothelial and mesenchymal cells in the cryopreserved suspension cells of human fetal liver. Also we observed epithelial-mesenchymal transition of hepatoblasts in culture. We show that it’s possible to apply the method of cryopreservation of hematopoietic cells of human fetal liver of the first gestation trimester for cryopreservation of parenchymal and stromal cells of fetal liver.

Keywords: hematopoietic stem cells, endothelial progenitor cells, mesenchymal stem cells, transdifferentiation, cell fusion