The most frequent chromosomal abnormalities in patients with reproductive problems

Tavokina L.V., Baronova E.V., Sopko N.I.

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Results of cytogenetic and molecular-cytogenetic inspection of 210 matrimonial pairs with the problems of reproduction are presented. Different types of chromosomal aberrations have been detected in the karyotypes of the patients in 46 (10,95 %) cases. Such structural chromosomal aberrations as pericentric inversions, Robertsonian translocations, balanced reciprocal translocations, and marker chromosomes as well prevailed the numerical chromosomal aberrations (89,13 and 10,87 % cases accordingly). In the general group of the inspected patients there were 19 cases (4,52 %) characterized by the low level of X and Y chromosome mosaicism. The authors suppose that the patients with the exposed chromosomal abnormalities need the differentiated approach at their treatment.

Tsitologiya i Genetika 2007, vol. 41, no. 4, pp. 48-55

Tavokina L.V., Baronova E.V., Sopko N.I. The most frequent chromosomal abnormalities in patients with reproductive problems, Tsitol Genet., 2007, vol. 41, no. 4, pp. 48-55.