Цитологія і генетика 1989, том 23, № 3, 3-7
Cytology and Genetics , том , № , , doi: https://www.doi.org/

Ультраструктурные изменения тромбоцитов при АДФ-стимулируемой агрегации (в присутствии фибриногена)

Белицер Н. В., Анищук М. Г., Позднякова Т. М., Горкун О. В.

The ultrastructure of resting and stimulated human blood platelets (P) was studied by the transmission electron microscopy. The cells were chemically fixed (using tannic acid and OsFeCN mixture) 1, 3, 5 and 15 min after the addition of ADP and fibrinogen (F). Early changes in P ultrastructure consist in drastic reduction of the electron-dense layer of glycocalyx and in an increase of the plasma membrane permeability. At the early stages of P aggregation the cells contact with each other due to rapidly arising pseudopodia. Later, the extracellular network containing an exogenous F participates in the aggregation process.

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Цитологія і генетика
1989, том 23, № 3, 3-7

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