Immunohistochemical and biochemical analysis of mammary gland tumours of different age patients

Immunohistochemical and biochemical study of infiltrative ductal breast carcinoma and tissue adjacent to the tumour revealed a particular molecular profile and characteristics of the oxidant-antioxidant status neoplasms depending on the age of the patients and the presence of metastases in regional lymph nodes. Some causes of high aggressiveness and low hormone sensitivity of tumours in premenopausal women, as well as stability and high metastatic potential of tumours in postmenopausal women have been found.

Keywords: breast tumours, the molecular profile, oxidant-antioxidant characteristics, metastasis, menopausal status