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Effects of oil-refining microbes (genus Acinetobacter) on cytogenetical structures of human lymphocytes in cellular cultures
Ilyinskikh N.N., Ilyinskikh E.N., Ilyinskikh I.N.
SUMMARY. The objective of this study was to assess ability of oil-refining bacteria Acinetobacter calcoaceticus and A. valentis to induce karyopathological abnormalities and chromosomal aberrations in human lymphocyte cultures. It was found that the cultures infected with A. calcoaceticus showed significantly high frequencies of cytogenetical effects and chromosomal aberrant cells as compared to the intact cultures and cultures infected with A. valentis. The most of chromosomal aberrations, mainly chromatid aberrations, were located in 1 and 2 chromosomes. Moreover, the aberrations were detected in some specific chromosome areas. Abnormalities of mitotic cell division and nucleus morphology were determined in lymphocyte cultures infected with A. calcoaceticus. There were found significantly high frequencies of cells with micronuclei, nucleus protrusions, anaphase or metaphase chromosome and chromosomal fragments lagging as well as multipolar and C-mitoses. Thus, the oil-refining bacteria A. calcoaceticus in contrast to A. valentis demonstrated strong genotoxic effects in human lymphocyte cultures in vitro.
Tsitologiya i Genetika 2012, vol. 46, no. 6, pp. 67-74
E-mail: ilyinskikh  yandex.ru
Ilyinskikh N.N., Ilyinskikh E.N., Ilyinskikh I.N. Effects of oil-refining microbes (genus Acinetobacter) on cytogenetical structures of human lymphocytes in cellular cultures, Tsitol Genet., 2012, vol. 46, no. 6, pp. 67-74.
In "Cytology and Genetics":
N. N. Ilyinskikh, E. N. Ilyinskikh, I. N. Ilyinskikh Effect of petroleum-destructing microorganisms (of the genus Acinetobacter) on the cytogenetic structures of human lymphocytes in cell cultures, Cytol Genet., 2012, vol. 46, no. 6, pp. 384-389
DOI: 10.3103/S0095452712060047
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