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Alternative mechanisms for telomere lengthening

Grach A.A.

Review 


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The review considers mechanisms of an alternative lengthening of telomeres (ALT) which posses the second after telomerase but not less important place in telomere length regulation. The general data about ALT are shown. An alternative lengthening of telomeres in normal and cancer cell lines are characterized. Special attention is given to the features of recombinational and retrotranspositional mechanisms of ALT.

Key words: telomeres, alternative lengthening of telomeres, recombination, retrotransposition

Tsitologiya i Genetika 2011, vol. 45, no. 2, pp. 69-81

E-mail: andry_gr mail.ru

Grach A.A. Alternative mechanisms for telomere lengthening, Tsitol Genet., 2011, vol. 45, no. 2, pp. 69-81.

In "Cytology and Genetics":
A. A. Grach Alternative telomere-lengthening mechanisms, Cytol Genet., 2011, vol. 45, no. 2, pp. 121-130
DOI: 10.3103/S0095452711020046

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