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Avermectin effects on ultrastructure characteristics of the loach embryos

Mandzynets S.M., Kulachkovsky O.R., Вura M.V.

 


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The ultrastructure of embryo cells of the loach (Misgurnus fossilis L.) at the stage of the first and the tenth divisions of blastomers in control and under the conditions of avermectin (0,01, 0,1 and 1 mg/ml) impact was investigated. Effect of avermectin resulted in significant ultrastructural changes of embryo cells such as hypertrophy of channels of the smooth and rough endoplasmic reticulum, disorganization of mitochondria and cytoplasm membrane destructions of the embryos. Avermectin led to disruption of Na+, K+ and Ca2+ active transport resulted in destructive changes in metabolic and regulation processes and embryo death. Such results show the high embryotoxicity of avermectin.

Key words: avermectin, ultrastructure, organells, plasma membrane, loach embryo

Tsitologiya i Genetika 2011, vol. 45, no. 5, pp. 58-64



Mandzynets S.M., Kulachkovsky O.R., Вura M.V. Avermectin effects on ultrastructure characteristics of the loach embryos, Tsitol Genet., 2011, vol. 45, no. 5, pp. 58-64.

In "Cytology and Genetics":
S. M. Mandzynets, O. R. Kulachkovskii, M. V. Bura Effect of avermectin on the ultrastructural characteristics of loach embryos, Cytol Genet., 2011, vol. 45, no. 5, pp. 318-323
DOI: 10.3103/S0095452711050070

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