ISSN 0564-3783  
Main page
Contacts
Preview papers  
Contents  
Themes
Subscription
Information to authors
Editorial board
Standard version



In Ukrainian

Export citations   UNIMARC   BibTeX   RIS


Association of P-mobile element activity and DNA methylation pattern changes at the conditions of Drosophila melanogaster prolonged irradiation

Kravets A.P., Mousseau T.A., Litvinchuk A.V., Ostermiller S.

 


[Free Full Text (pdf)]Article Free Full Text (pdf)  

Association of the radiosensitivity and epigenetic pattern DNA changes at the conditions of prolonged irradiation was investigated. Two laboratory Drosophila melanogaster strains (Canton-s and ri) irradiated for 20 generations to low doses rate (1,2 108, 0,8 108 and 0,12 108 Gy/s) were used as experimental objects. DNA for the analysis was extracted separately for the flies of males and females. Restriction endonucleases GluI, GlaI were used. Restriction analysis has shown that there are different DNA methylated patterns for males and females as for control and exposed variants. At the chronic irradiation there was the decline of methylation level at the enzymes GluI, GlaI sites recognition.

Tsitologiya i Genetika 2010, vol. 44, no. 4, pp. 29-33

E-mail: kravetsap yahoo.com

Kravets A.P., Mousseau T.A., Litvinchuk A.V., Ostermiller S. Association of P-mobile element activity and DNA methylation pattern changes at the conditions of Drosophila melanogaster prolonged irradiation, Tsitol Genet., 2010, vol. 44, no. 4, pp. 29-33.




Copyright© ICBGE 2002-2021 Coded & Designed by Volodymyr Duplij Modified 29.11.21