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The molecular biology diagnosis of neoplastic blood diseases

Teleheiev H.D., Dybkov M.V., Bozhko M.V., Tretiak N.M., Maliuta S.S.

 




Molecular-biological approaches was applied for detection of Philadelphia chromosome in patients with chronic myeloid and acute lymphoblastic leukemias. It includes bcr-genomic probes and polymerase chain reaction with specific bcr/abl primers. The latter is m c86 ore preferable for clinic use. Different diagnostic methods are compared and leukemias etiology problems are discussed.

Tsitologiya i Genetika 1998, vol. 32, no. 1, pp. 71-78



Teleheiev H.D., Dybkov M.V., Bozhko M.V., Tretiak N.M., Maliuta S.S. The molecular biology diagnosis of neoplastic blood diseases, Tsitol Genet., 1998, vol. 32, no. 1, pp. 71-78.




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