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The Phenthiuram Induction of Micronuclei in Mammalian Somatic Cells

Bakhitova L. M., Pashin Yu. V.

 




Genotoxic effects of the preparative-form phenthiuram on the induction of micronuclei in cultured Chinese hamster V-79 cells and polychromatic erythrocytes of mouse bone marrow have been studied. The phenthiuram induced cytogenetic effects in cultured somatic cells without metabolic activation being only in toxic concentrations. Similar effects were observed in polychromatic erythrocytes after treatment with subtoxic concentrations.

Tsitologiya i Genetika 1987, vol. 21, no. 1, pp. 54-57



Bakhitova L. M., Pashin Yu. V. The Phenthiuram Induction of Micronuclei in Mammalian Somatic Cells, Tsitol Genet., 1987, vol. 21, no. 1, pp. 54-57.




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