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Cytogenetic Activity of Certain Chemicals in Adrenalectomized Rats

Barilyak I. R., Saglo V. I.

SUMMARY. Pyrimethamine, sodium salicylate or ethanol were administered to adrenalectomized rats 3 and 21 days after the operation. It is shown that cytogenetic effect in the operated rats is less pronounced, particularly 3 weeks after the operation. Adrenalin (0.2 mg/kg) increases the effect of chemicals on the chromosome apparatus, while hydrocortisone (50 mg/kg) and corticotropin (10 U/kg) decrease it.

Tsitologiya i Genetika 1987, vol. 21, no. 5, pp. 343-349

Barilyak I. R., Saglo V. I. Cytogenetic Activity of Certain Chemicals in Adrenalectomized Rats, Tsitol Genet., 1987, vol. 21, no. 5, pp. 343-349.