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Cytokine profiles in mice tissues after irradiation of thymus projection area with femtosecond laser

Kanevskyi V.A., Pushkarev V.M.

 




SUMMARY. We study the effects of pulsed femtosecond laser irradiation in the near ultraviolet region on the levels of cytokines in the thymus, blood and skin of irradiated mice. Irradiation of the thymus projection area with low-intensity laser radiation in the near UV region of the spectrum showed significant changes in cytokine levels in the skin and thymus and, to a lesser extent, in the blood of irradiated mice. Laser irradiation with a power density of 20 mW/cm2 affects the cytokine profile in the thymus: IFN-γ, IL-3, IL-4, IL-5, eotaxin, GM-CSF and KC ‒ factors that can affect differentiation and proliferation of the cells of the immune system in the gland. It is assumed that changes in the expression of cytokines in the thymus after laser irradiation are explained by the rearrangement of biochemical processes possibly associated with the maturation of cells in the gland.

Tsitologiya i Genetika 2017, vol. 51, no. 6, pp. 58-68

E-mail: pushkarev.vm gmail.com

Kanevskyi V.A., Pushkarev V.M. Cytokine profiles in mice tissues after irradiation of thymus projection area with femtosecond laser, Tsitol Genet., 2017, vol. 51, no. 6, pp. 58-68.




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