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Analysis of molecular-genetic study of the polymorphic locus C-159T CD14 gene in children with increased risk of recurrent episodes of acute obstructive bronchitis

Kens O., Gnateyko O., Lukyanenko N., Vishtak N., Bergtravm V.

 




SUMMARY. A molecular genetics study of polymorphic locus C-159T CD14 gene in 31 children with recurrent episodes of acute obstructive bronchitis and 50 of human beings taken by random sampling, that are included in a control group. The study did not record statistically probable increased frequency of genotypes CC, CT and TT polymorphic locus C-159T CD14 gene among children of the main group compared with the control group. However, there is a trend toward more frequent occurrence of TT genotype of the polymorphic locus C-159T CD14 ge-ne among children with recurrent episodes of acute bronchitis than in control group (32,25 % vs. 22,0 %).

Key words: recurrent episodes of acute obstructive bronchitis, acute respiratory infections, children, molecular genetic analysis, gene polymorphism

Tsitologiya i Genetika 2017, vol. 51, no. 5, pp. 55-61

E-mail: ovkens gmail.com

Kens O., Gnateyko O., Lukyanenko N., Vishtak N., Bergtravm V. Analysis of molecular-genetic study of the polymorphic locus C-159T CD14 gene in children with increased risk of recurrent episodes of acute obstructive bronchitis, Tsitol Genet., 2017, vol. 51, no. 5, pp. 55-61.

In "Cytology and Genetics":
O. V. Kens, O. Z. Gnateyko, N. S. Lukyanenko, N. V. Vishtak, V. I. Bergtravm Analysis of molecular genetic study on the polymorphic C-159T locus of the CD14 gene in children with increased risk of recurrent episodes of acute obstructive bronchitis, Cytol Genet., 2017, vol. 51, no. 5, pp. 365–370
DOI: 10.3103/S0095452717050036


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