Cytology and Genetics 2012,
vol. 46,
no. 4, 220-226,
doi: https://www.doi.org/10.3103/S009545271204010X
SUMMARY. In this study analysis of single nucleotide polymorhisms A351G, С397Т and number of ТА-repeats in ESR1 gene among 199 healthy volunteers from Ukraine was performed. Data concerning genotypes and particular alleles of polymorphic variants distribution were obtained. Possible mechanisms of these polymorphic variants role in ESR1 gene transcription and estrogen receptor expression changes are being discussed.
Keywords: estrogen receptor, DNA-polymorphisms, ESR1 gene, population