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Peculiarities of urinary bladder cancer tumor cells apoptosis response on neoadjuvant chemotherapy

Yatsyna O.I., Stakhovsky E.A., Sheremet Ya.A., Spivak S.I., Stakhovsky A.E., Gavryluk O.M., Vytruk Yu.V., Yemets A.I., Blume Ya.B.

 


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Induced apoptosis in urinary bladder cancer tumor cells of patients was studied using TUNEL reaction. It was shown that increase in induced apoptosis value had a definite correlation between corresponding features of tumor reaction as a response on Gemcitabine-Cisplatin neoadjuvant chemotherapy application. It was found that evaluation of induced apoptosis in urinary bladder cancer tumor cells using TUNEL method allows forecasting the effectiveness of chemotherapy on the cellular level in patients with this type of cancer.

Tsitologiya i Genetika 2011, vol. 45, no. 4, pp. 3-8

E-mail: yatsyna gmail.com

Yatsyna O.I., Stakhovsky E.A., Sheremet Ya.A., Spivak S.I., Stakhovsky A.E., Gavryluk O.M., Vytruk Yu.V., Yemets A.I., Blume Ya.B. Peculiarities of urinary bladder cancer tumor cells apoptosis response on neoadjuvant chemotherapy, Tsitol Genet., 2011, vol. 45, no. 4, pp. 3-8.

In "Cytology and Genetics":
O. I. Iatsyna, E. O. Stakhovsky, Ya. A. Sheremet, S. I. Spivak, O. E. Stakhovsky, O. N. Gavrilyuk, Yu. V. Vitruk, A. I. Emets, Ya. B. Blyum, S. V. Vernygorodskyi Specific features of the apoptotic response of urinary bladder cancer cells to neoadjuvant chemotherapy, Cytol Genet., 2011, vol. 45, no. 4, pp. 201-207
DOI: 10.3103/S0095452711040128


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