Kovaleva O.A.

Cytogenetic abnormalities in mammalian somatic cells

Cytology and Genetics 2008, v 42, number 1, 58-72

The different types of cytogenetic abnormalities are considered which are used in classic cytogenetics for the estimation of the levels of chromosome apparatus damages. The possible causes of cytogenetic anomalies and a number of methods of micronucleus tests are discussed. It was shown that the different levels of genetic material organization influence the realization of DNA defects into cytogenetic abnormality.