Sergienko I.V., Gupal A.M., Vagis A.A.

Complementary principles of bases recoding along one chain of DNA

Cytology and Genetics 2005, v 39, number 6, 71-75

We have determined the new complementary principles in encoding bases on DNA chain in chromosomes of human genome and some other investigated genomes. The obtained results show that regularity analogues to Chargaff rule (or complementary principle of Watson-Crick) holds not only for two-chain DNA spiral but even for each separate chain. Moreover, we revealed other remarkable regularities concerning repeating sequences of sets of identical letters (bases). On the basis of obtained statistical data one can draw a conclusion that there exist some strict rules of forming DNA structure valid for all species. The obtained results will significantly improve our present view of encoding genetic information and also data on DNA replication process as well as formation of compact shape of chromosome packing.