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Gubenko I.S.

Locus Delta in the Notch Signaling System: Organization and Pleiotropic Function during Drosophila Development

Cytology and Genetics 2001, v 35, number 4, 59-80


Delta locus is the important component of the Delta-Notch signaling system implicating in a general mechanism of local cell signaling. Delta and Notch encode the evolutionary conserved cell surface proteins that interact and function as ligand (DELTA) and receptor (NOTCH) in a wide variety of cell fate specification events during oogenesis, embryogenesis and metamorphosis.




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