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In Russian



Pilinskaya M.A., Dybskiy S.S.

The Frequency of Stable Chromosome Aberrations Determined by FISH Method in 49 Liquidators of the Chernobyl Accident with Various Exposure Doses

Cytology and Genetics 2001, v 35, number 4, 50-54


FISH technique was tested on the 49 liquidators of the Chernobyl Accident. Groups were formed according to average group exposure doses and/or individual ones determined by the method of EPR. The essential variability of spontaneous and irradiation-induced frequencies of reciprocal translocations was observed. In groups with the lowest EPR-doses (below 25 cGy) the average cytogenetic dose was considerably higher then doses determined by EPR-method. The best coincidences between average in-group EPR- and FISH-doses were in the group with 25-50 cGy doses for “acute irradiation” model and in the group with 50-100 cGy and higher for “chronic irradiation” model.




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