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Bariliak I.R., Frolov V.M., Pinskiy LL, Topol’nitskiy V.S.
Cytogenetic disorders iin patients with chronic hepatitis B and C
Cytology and Genetics 2000, v 34, number 4, 3-5
The chromosomal apparatus of peripheral blood lymphocytes was studied in 19 patients with chronic hepatitis B (CHB) and 17 patients with chronic hepatitis C (CHC). Significant changes in cytogenetic indices were revealed in the both groups. Incidence of aberrant cells in CHC exceeded significantly that in CHB (15.3 +/- 1.5% vs 11.1 +/- 0.9% respectively; P < 0.05). Frequencies of aberration per cell and chromatid fragments were also significantly higher in CHC compared with both CHB and practically normal donor groups.
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