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Comparison of the possibilities of micronuclear and chromosomal aberration tests for evaluation of the effects of radiation of different intensities

Shemetun G.M., Pilins’ka M.A., Ieremieieva M.M.

 




The comparative evaluation of sensitivity and specificity of the micronucleus and chromosome aberration tests for human lymphocytes at the delayed terms after acute exposure to high-dose as well as during constant exposure to low-dose gamma-radiation has been done. Accordance between these tests registered only in the cases of acute radiation sickness of second and third degrees of severity (irradiation doses above 200 cGy). Unspecificity of micronucleus test for estimation of the radiation load under constant low-intensity irradiation was found.

Tsitologiya i Genetika 2000, vol. 34, no. 5, pp. 3-10



Shemetun G.M., Pilins’ka M.A., Ieremieieva M.M. Comparison of the possibilities of micronuclear and chromosomal aberration tests for evaluation of the effects of radiation of different intensities, Tsitol Genet., 2000, vol. 34, no. 5, pp. 3-10.




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