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The HLA system antigens in delayed sexual development

Bagatskaia N.V., Krivich I.P., Demenkova I.G., Kovaleva V.I.

 




Frequency distribution of HLA antigens of A and B loci was examined in 138 adolescent boys aged 14-18 with delayed sexual development (DSD) of stages I-III, residing in the north-eastern region of Ukraine. Increase of A28- and B40-antigens and haplotypes A1-B40, A28-B40, A10-B40 determination frequencies was established. There were revealed positive and negative correlation between some of HLA antigens and DSD. Relative and attributive risks of DSD formation were calculated.

Tsitologiya i Genetika 2000, vol. 34, no. 1, pp. 43-47



Bagatskaia N.V., Krivich I.P., Demenkova I.G., Kovaleva V.I. The HLA system antigens in delayed sexual development, Tsitol Genet., 2000, vol. 34, no. 1, pp. 43-47.




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