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Teleheiev H.D., Dybkov M.V., Bozhko M.V., Tretiak N.M., Maliuta S.S.
The molecular biology diagnosis of neoplastic blood diseases
Cytology and Genetics 1998, v 32, number 1, 71-78
Molecular-biological approaches was applied for detection of Philadelphia chromosome in patients with chronic myeloid and acute lymphoblastic leukemias. It includes bcr-genomic probes and polymerase chain reaction with specific bcr/abl primers. The latter is m c86 ore preferable for clinic use. Different diagnostic methods are compared and leukemias etiology problems are discussed.
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