Main page
Contacts
Contents
Themes
Subscription
Information to authors
Editorial board
|  |
Salamanchuk Z.Ia., Masliak Z.V., Lozyns’ka M.R., Vyhovs’ka Ia.I., Lohins’kyy V.Ie., Male P.
Karyotype studies of patients with a myelodysplastic syndrome
Cytology and Genetics 1998, v 32, number 1, 43-48
Cytogenetic investigations, including the analysis of karyotype indicated by G-banding and FISH for Ph chromosome, were performed in the patients with myelodysplastic syndrome (MDS), classified according to FAB system. In RA we have not revealed any important karyotype abnormalities. In patients with RAEB we have detected monosomy 7, considered an c86 unfavourable prognostic sign. There was found an unidentified marker chromosome in the patient with CMML. Diagnostic and prognostic value of karyotype investigation in MDS patients was discussed.
|
