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Isakova LM, Ganina KP, Ivanova IM, Vakulenko GA
The cytological characteristics of the cells of the multilayer squamous epithelium of the cervix uteri in relation to the association of the pathological processes with the human papilloma virus
Cytology and Genetics 1997, v 31, number 6, 3-11
An analysis of cytological material in benign (160 observations) and dysplastic (101 observations) processes, as well as in cervix outset cancer (38 observations) with the aim of search for koilocytic atypia markers in the cells, existing due to HPV infection, has been carried out. High association degree of the virus infection with the material under study has been ascertained. It was found out that the increase of koilocytosis phenotypic markers expression rate is a reliable criterion of cervix uteri pathologic processes progression. The signs of permanent koilocytic atypia in women with dysplasia should be considered as prognostic marker of malignant transformation of cervix uteri epithelium.
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