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Maliarchuk BA

MtDNA-like sequences and the coordination of the functioning of mammalian nuclear and mitochondrial genomes

Cytology and Genetics 1997, v 31, number 2, 53-61


Mitochondrial DNA-like sequences in the nuclear genome of mammals are classified in two types: ontogenetic and evolutionary. Mechanisms of the transfer of DNA from mitochondria into nucleus and transformation of the ontogenetic mtDNA-like sequences to evolutionary ones are discussed. The origin of short sequences of DNA common to nuclear and mitochondrial genome and the role of these sequences in the coordination of gene expression have received much attention.




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