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The Effect of Hyperbaric Oxygenation on Survival Rate, Mutagenesis and Recombinogenesis of One-Celled Organisms

Guskov E. P., Pavlov Yu. I., Ter-Avanesyan M. D., Chistyakov V. A.

 




The hyperbaric oxygenation (HBO) has been studied for its ability to induce the cell death and different genetic variations in normal and repair defective strains of bacteria (Escherichia coli and Salmonella typhimurium) and of yeast (Saccharomyces cerevisiae) strains with different ploidy. HBO is shown to induce an increase in the mutability of excision-repair defective strains and a decrease in the survival rate of error-prone repair defective strains of the procaryote. HBO is a weak recombinogen for yeast and induces no mutations of the haploid strain. The results obtained reflect doubt on the community of the mechanisms of radiation and HBO actions on the cell.

Tsitologiya i Genetika 1987, vol. 21, no. 1, pp. 10-15



Guskov E. P., Pavlov Yu. I., Ter-Avanesyan M. D., Chistyakov V. A. The Effect of Hyperbaric Oxygenation on Survival Rate, Mutagenesis and Recombinogenesis of One-Celled Organisms, Tsitol Genet., 1987, vol. 21, no. 1, pp. 10-15.




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